Mike Pelfrey gave New York's injury-riddled pitching staff an encouraging boost, and the Philadelphia Phillies played a painfully sloppy game in the Mets' 8-2 victory in the National League on Wednesday.
The Mets ended a nine-game losing streak to Philadelphia, taking advantage of four errors that led to six unearned runs.
Handed a comfortable lead, Pelfrey (1-0) tossed five effective innings in his first start of the year.
Angel Pagan hit a two-run double for the Mets. Damion Easley, starting at second base for ailing Luis Castillo, put New York ahead 2-1 with an RBI single off Kyle Kendrick (1-1) in the third. Kendrick walked six batters in the first two innings.
The Phillies' MVP shortstop Jimmy Rollins sat out with a sprained left ankle, missing his first game since July 30, 2006.
Diamondbacks 4, Dodgers 3
At Phoenix, Eric Byrnes hit a go-ahead, two-run single in the seventh-inning off Hiroki Kuroda, and Arizona stretched its winning streak to six.
Micah Owings (2-0) allowed three runs and seven hits in seven innings as the Diamondbacks finished a three-game sweep of their NL West rival Los Angeles.
Byrnes, who went 3-for-5, ended Kuroda's afternoon with a two-out, bases-loaded single that brought in the tying and go-ahead runs in the sixth.
Kuroda (1-1), in his second start since coming to the Dodgers from Japan, gave up four runs _ two earned _ and nine hits in 5 2-3 innings.
Marlins 10, Nationals 4
At Washington, Mike Jacobs hit two homers, including one that capped a seven-run inning, to back Scott Olsen's solid pitching and help Florida beat Washington, which has lost six consecutive games after a 3-0 start to the season.
The pair of two-run shots give the first baseman four homers in the past five games.
Olsen (1-0) went 7 2-3 innings, allowing four runs _ three earned _ and four hits.
Nationals starter Jason Bergmann (0-1) managed to fool Florida for four innings. He got hit hard in the fifth, as the Marlins sent 10 men to the plate and scored seven runs, all earned.
Rockies 12, Braves 6
At Denver, Yorvit Torrealba hit a three-run home run to cap off a six-run third inning and Colorado put up its highest run total of the young season to win its third straight.
Matt Holliday had a triple and two RBIs and Ryan Spilborghs went 3-for-5 with a home run and five RBIs in a spot start.
Mark Redman (1-1) pitched five innings and allowed three runs _ two earned _ and seven hits.
Chuck James (0-1), who was activated from the 15-day disabled list before the game, gave up six runs in three innings in his first start of the season. James hit three batters.
Cubs 6, Pirates 4, 15 innings
At Pittsburgh, Felix Pie's two-run single in the 15th allowed Chicago to outlast Pittsburgh in the second extra-inning game in a row between them.
Pie's hit to left off of Phil Dumatrait (0-1) with the bases loaded scored Ryan Theriot and Alfonso Soriano, helping the Cubs win their fourth in a row.
Twice the Pirates tied the Cubs with home runs to extend the game. Jason Bay hit his first of the season to lead off the ninth against Kerry Wood, who blew his first save. Adam LaRoche then broke out of an 0-for-25 slump by homering off of Kevin Hart (2-0) with Bay aboard in the 14th to tie the game at 4.
That came after ex-Pirate Aramis Ramirez had given the Cubs the lead with a two-run shot, his second, in the top of the inning. Ramirez had three hits and scored two runs.
Cardinals 6, Astros 4
At Houston, Albert Pujols hit his first two homers of the year and St. Louis beat Houston to take its third straight series.
Pujols also had a RBI single and Rick Ankiel added two RBIs.
St. Louis opened the season with series wins over Colorado and Washington before taking this one 2-1. They won three consecutive series' just once last season.
Reds 12, Brewers 4
At Milwaukee, Adam Dunn and Corey Patterson each hit two-run homers, Brandon Phillips scored twice off a pair of heady baserunning plays and Cincinnati scored 10 straight runs in a victory over Milwaukee.
Phillips compensated for allowing two unearned runs that cost Cincinnati the lead in the fifth when he let a grounder go through his legs.

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